If, forever what reason, you have a WSUS server running on the server where your CA also resides and you remove the WSUS role from the server you end up with a broken certsrv website for the CA. WSUS enables 64-bit compression that causes any 32-bit applications running in IIS to fail.
To get your certsrv website running again open an elevated command prompt, go to the inetsrv directory (default is c:\windows\system32\inetsrv) and enter the following command:
appcmd.exe set config -section:system.webserver/httpCompression /-[name=’xpress’]
